What Are The Factors That Cause
Skin Irritation and Dryness
The contributing factors affecting the drying and irritancy cleansers stem from the type and rinsability of surfactant ingredients, and lesser degree of pH. Take note that surfactants after binding to keratin may cause protein denaturation, which may lead to damage to the cell membrane of keratinocytes and adverse cutaneous responses.
Further, surfactant chain length is also a crucial consideration in assessing the irritant potential with Kellum. Even if the anionic surfactants are deemed to have caused the greatest irritancy potential, their use in a cleansing agent and their combination with cationic acrylate changes the irritation potential.